Precocious Pubarche in a 7-Year-Old Patient. A Case Report

Abstract

We present the case of a 7-year and 9-month-old female patient who visited the Pediatric clinic due to the onset of pubarche at seven years and seven months of age. There is no observed increase in body odour, axillary hair growth, or mastodynia. The mother reports an acceleration in growth velocity over the past few months. The child maintains a proper diet, is physically active, and demonstrates good academic performance. Regarding her personal history, she was born from a controlled gestation and eutocic delivery induced at 39 weeks, with a birth weight of 2,960 kilograms and no neonatal complications. Endocrine-metabolic screening yielded negative results, and she has no known allergies or relevant prior illnesses. In terms of family history related to early development, the mother reported menarche at 10.5 years and hirsutism since childhood. Additionally, there were ovulation issues, and the second child was conceived through artificial insemination. The mother is also a carrier of an unknown type of muscular atrophy. The pubertal development of the father remains unknown. The patient’s 12-year-old brother is in good health. Anthropometric measurements and evaluation of adult height were conducted. During the physical examination, the patient exhibited a normal phenotype, without goitre or palpable thyroid. The Tanner stage was G1M1P2. A hormonal study and wrist X-ray for bone age assessment were requested, and the results were within normal limits. Consequently, the patient received a diagnosis of Isolated Premature Pubarche, and a quarterly outpatient follow-up was scheduled